Browsing by Author "Holst, Rene"

Now showing items 1-3 of 3

    • Impulsivity across severe mental disorders: a cross-sectional study of immune markers and psychopharmacotherapy 

      Hjell, Gabriela; Rokicki, Jaroslav; Szabo, Attila; Holst, Rene; Tesli, Natalia; Bell, Christina; Fischer-Vieler, Thomas; Werner, Maren Caroline Frogner; Lunding, Synve Hoffart; Elkjær Greenwood Ormerod, Monica Bettina; Johansen, Ingrid Torp; Djurovic, Srdjan; Ueland, Thor; Andreassen, Ole; Melle, Ingrid; Lagerberg, Trine Vik; Mørch-Johnsen, Lynn Egeland; Steen, Nils Eiel; Haukvik, Unn Kristin Hansen (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-09-07)
      Background Impulsivity is a transdiagnostic feature linked to severe clinical expression and a potential target for psychopharmacological strategies. Biological underpinnings are largely unknown, but involvement of immune dysregulation has been indicated, and the efects of psychopharmacological agents vary. We investigated if impul‑ sivity was associated with circulating immune marker levels and ...

    • Interleukin-18 signaling system links to agitation in severe mental disorders 

      Hjell, Gabriela; Szabo, Attila; Mørch-Johnsen, Lynn Egeland; Holst, Rene; Tesli, Natalia; Bell, Christina; Fischer-Vieler, Thomas; Werner, Maren Caroline Frogner; Lunding, Synve Hoffart; Ormerod, Monica Bettina E. Greenwood; Johansen, Ingrid Torp; Dieset, Ingrid; Djurovic, Srdjan; Melle, Ingrid; Ueland, Thor; Andreassen, Ole; Steen, Nils Eiel; Haukvik, Unn Kristin Hansen (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-12)
      Objective: Agitation is a challenging clinical feature in severe mental disorders, but its biological correlates are largely unknown. Inflammasome-related abnormalities have been linked to severe mental disorders and implicated in animal models of agitation. We investigated if levels of circulating inflammasome-related immune markers were associated with agitation in severe mental disorders.<p> ...

    • SARS-CoV-2 vaccines are not associated with hypercoagulability in apparently healthy people 

      Garabet, Lamya Samir Noori; Eriksson, Anna Maria; Tjønnfjord, Eirik; Cui, Xueyan; Olsen, Magnus Kringstad; Jacobsen, Hege; Jørgensen, Camilla Tøvik; Mathisen, Åse-Berit; Mowinckel, Marie-Christine; Ahlen, Maria Therese; Sørvoll, Ingvild Hausberg; Horvei, Kjersti Daae; Ernstsen, Siw Leiknes; Lægreid, Ingvild Jenssen; Stavik, Benedicte; Holst, Rene; Sandset, Per Morten; Ghanima, Waleed (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-25)
      Background: SARS-CoV-2 adenoviral vector DNA vaccines have been linked to the rare but serious thrombotic postvaccine complication vaccine-induced immune thrombotic thrombocytopenia. This has raised concerns regarding the possibility of increased thrombotic risk after any SARS-CoV-2 vaccines. <p><p>Objectives: To investigate whether SARS-CoV-2 vaccines cause coagulation activation leading to a ...